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UnderstandingBioinformatics
生物信息学的圣经,作为教程值得一度Suitableforadvancedundergraduatesandpostgraduates,UnderstandingBioinformaticsprovidesadefinitiveguidetothisvibrantandevolvingdiscipline.Thebooktakesaconceptualapproach.Itguidesthereaderfromfirstprinciplesthroughtoanunderstandingofthecomputationaltechniquesandthekeyalgorithms.UnderstandingBioinformaticsisaninvaluablecompanionforstudentsfromtheirfirstencounterwiththesubjectthroughtomoreadvancedstudies.Thebookisdividedintosevenparts,withtheopeningpartintroducingthebasicsofnucleicacids,proteinsanddatabases.Subsequentpartsaredividedinto'Applications'and'Theory'Chapters,allowingreaderstofocustheirattentioneffectively.Ineachsection,theApplicationsChapterprovidesafastandstraightforwardroutetounderstandingthemainconceptsand'gettingstarted'.EachoftheseisthenfollowedbyTheoryChapterswhichgivegreaterdetailandpresenttheunderlyingmathematics.InPart2,SequenceAlignments,theApplicationsChaptershowsthereaderhowtogetstartedonproducingandanalyzingsequencealignments,andusingsequencesfordatabasesearching,whilethenexttwochapterslookcloselyatthemoreadvancedtechniquesandthemathematicalalgorithmsinvolved.Part3coversevolutionaryprocessesandshowshowbioinformaticscanbeusedtohelpbuildphylogenetictrees.Part4looksatthecharacteristicsofwholegenomes.InParts5and6thefocusturnstosecondaryandtertiarystructure–predictingstructuralconformationandanalysingstructure-functionrelationships.Thelastpartsurveysmethodsofanalyzingdatafromasetofgenesorproteinsofanorganismandisroundedoffwithanoverviewofsystemsbiology.ThewritingstyleofUnderstandingBioinformaticsisnotableforitsclarity,whiletheextensive,full-colorartworkhasbeendesignedtopresentthekeyconceptswithsimplicityandconsistency.Eachchapterusesmind-mapsandfl
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